MedChemComm View Article Online Published on 01 August 2014. The core therapeutic focus of our company is obesity, Type II diabetes / metabolic syndrome, inflammatory diseases, and organ protection in severe cardiovascular diseases such as myocardial infarction and post-surgical organ failure. Submit a Company Alliance strengthens both Companies' oncology pipelines. Roche Group Pharmaceuticals pipeline. We have three endocrinology rare disease product candidates in clinical development, and a pipeline of oncology candidates closely following. [3] Products on the veterinary market includes the adjuvant for the leading horse influenza vaccine. Abstract: The present invention relates to very short heavily modified oligonucleotides which target and inhibit microRNAs in vivo, and their use in medicaments and pharmaceutical compositions. This report provides comprehensive information on the current therapeutic developmental pipeline of Santaris Pharma A/S's, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism . Santaris Pharma was acquired by Roche in 2014 for $450M. Acute & chronic kidney injury We focus on a very specific protein (undisclosed) that plays a major role in inflammation / fibrosis. Contact Email info@santaris.com Phone Number (454)517-9800 Santaris Pharma A/S is a privately held clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. The Company is biology-driven with proprietary technology and a strong focus on product development. HORSHOLM, Denmark, July 14 -- The Board of Directors of Santaris Pharma has approved the Interim Report for the period 1 January to 30 June 2009. We are pleased to announce that Sporos BioDiscovery presented preclinical data on SPR1, a novel TEAD inhibitor program, at EORTC-NCI-AACR Symposium in Barcelona. This research strategy is generating a new clinical programme every year and continues to yield novel and proprietary drug targets, key to a more effective development of novel therapies. The vaccine would be safer, easier to administer and more cost effective than other potential drug candidates currently under development. | Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted therapies, announced that it has advanced a second drug from its cardiometabolic programme, SPC4955 into phase I clinical trials, for the treatment of high cholesterol. Investors eagerly await updates on the pipelines of pharma/biotech companies. Zealand Pharma is a biotechnology company focused on the discovery, design and development of innovative peptide-based medicines. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Merck's stock went from $48 at the end of 2014 to $90 at the end of 2019, representing a change of 87.5%. Santaris' pipeline of RNAi - or ' gene silencing ' - drugs are based on its Locked Nucleic Acid (LNA) platform and its lead candidate is miravirasen, a novel hepatitis C treatment in phase II trials. Arexis AB, founded by experienced scientists in 1999, is a drug discovery and development company focusing on metabolic and inflammatory diseases. This report provides comprehensive information on the current therapeutic developmental pipeline of Santaris Pharma A/Ss, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. Importantly . [3] For further information, please contact Santaris Pharma: Dr Keith McCullagh, President & CEO, Santaris Pharma A/S, Copenhagen, Denmark. The LNA Drug Platform and Drug Discovery Engine developed by Santaris Pharma A/S combine the companys proprietary LNA chemistry with its highly specialized and targeted drug development. Phase 1 clinical study to assess safety and tolerability of SPC4955, a drug inhibiting synthesis of apolipoprotein B (apoB), a major protein component involved in the . IsconovaSwedenAcquiredVaccines for veterinary and human use. The top players in pharma know how to adapt. Twitter Santaris, a privately held biopharmaceutical company based near Copenhagen, Denmark, has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. This research strategy is generating a new clinical programme every year and continues to yield novel and proprietary drug targets, key to a more effective development of novel therapies. /PRNewswire/ -- Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted. The Company is biology-driven with proprietary technology and a strong focus on product development. Santaris Pharma A/S was a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. Santaris Pharma A/S - Product Pipeline Review - 2014 NOXXON Pharma AG (Berlin, Germany) based on one of the biggest and best protected patent portfolios in the industry, Berlin-based NOXXON Pharma AG develops biostable aptamers, novel substances based on mirror image nucleic acids. Type: Grant. Name of the organization that made the acquisition, Total amount raised across all funding rounds, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Descriptive keyword for an Organization (e.g. Arexis uses forward genetics for a high-resolution molecular dissection of causative disease mechanisms. Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. Santaris Pharma A/S - Product Pipeline Review - 2014 is a new market research publication announced by Reportstack. LinkedIn Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. The target has been validated in in-vivo models & human pathological material. PDF. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. Date of Patent: December 9, 2014. Santaris Pharma is using LNA to make novel, highly potent and stable RNA Antagonists. Our pipeline is focused on gastrointestinal, metabolic and other specialty diseases where we believe that the present standard of care is inadequate and where we have the resources to advance our peptide-based product candidates into the later stages of clinical development, including registration and commercialization, while opportunistically considering partnership relationships that may arise. Request Profile Update capabilities to rapidly deliver potent single-stranded LNA-based drug candidates across a multitude of disease states. Continue reading on Roche.com: Locked Nucleic Acid (LNA) Platform. santaris pharma a/s has a robust product pipeline based on its proprietary lna technology including mrna and microrna drug discovery and development partnerships and collaborations with shire (rare genetic disorders), wyeth, now part of pfizer, (delivery of lead candidates against up to ten targets), glaxosmithkline (four viral disease drug Contact us at the Consulting WP office nearest to you or submit a business inquiry online. Santaris Pharma A/S - Product Pipeline Review - 2014 is a new market research publication announced by Reportstack. CARY, N.C., U.S.A. (March 28, 2022) - Veloxis Pharmaceuticals, Inc., an Asahi Kasei company, today announced initiation of study drug dosing in ART-123.PN101, a phase 1 study designed primarily to assess the safety and tolerability of ART-123 (thrombomodulin . Santaris Pharma A/S - Product Pipeline Review - 2014. Santaris Pharma: Company in Denmark, Europe. Efficacy studies in HCV infected chimpanzee with 12 weekly intravenous dosing with miravirsen found a marked and lasting decline of the viral titer [95]. WhatsApp acquired by Facebook). Access Full Search Results with a Business Account or On Demand Pass, About Us Swiss Therapeutics company developing therapies to treat severe neurological disorders. Santaris Pharma A/Swas a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. Associated sectors: Pharmaceuticals; Life sciences; Life Sciences - Pharma; Biotech; Life Science; Biotechnology; Healthcare - Drug development; Biopharmaceuticals; Healthtech; Healthcare; Life Sciences Companies - Drug Discovery and Development; Action PharmaDenmarkAcquiredAction Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. Roche (SIX: RO, ROG; OTCQX: RHHBY) has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. Santaris Pharma A/S advances a second drug from its cardiometabolic program, SPC4955, inhibiting apoB, into Phase 1 clinical trials for the treatment of high cholesterol. PDF. Santaris Pharma's operations in Denmark will be renamed Roche Innovation Center Copenhagen. (When Cookies Enabled), Santaris Pharma A/S is a clinical stage biopharmaceutical company developing next generation RNA-silencing drugs for the treatment of cancer and metabolic diseases. Summary Directory of Companies. By using its proprietary Locked Nucleic Acid (:LNA) platform and tissue-targeting expertise, Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or . The Roche Innovation Center in Copenhagen, originating from the acquisition of Santaris Pharma in 2014, is a leader in the rapidly emerging field of RNA-targeted drugs. Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. - The report provides brief overview of Santaris Pharma A/S including business description, key information and facts, and its locations and subsidiaries, - The report reviews current pipeline of Santaris Pharma A/Ss human therapeutic division and enlists all their major and minor projects, - The report features product description and descriptive mechanism of action for key pipeline products along with the products developmental history and major milestones, - Special feature on out-licensed and partnered product portfolio, - The report summarizes all the dormant and discontinued pipeline projects, - Latest news and deals relating to the Santaris Pharma A/Ss pipeline products, - Evaluate Santaris Pharma A/Ss strategic position with total access to detailed information on its product pipeline, - Assess the growth potential of Santaris Pharma A/S in its therapy areas of focus, - Identify new drug targets and therapeutic classes in the Santaris Pharma A/Ss R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas, - Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps, - Develop strategic initiatives by understanding the focus areas of Santaris Pharma A/S and exploit collaboration and partnership opportunities, - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage, - Plan mergers and acquisitions effectively by identifying the most promising pipeline of Santaris Pharma A/S, - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope, - Explore the dormant and discontinued projects of Santaris Pharma A/S and identify potential opportunities in those areas, - Avoid Intellectual Property Rights related issues, Pharma Pipeline Review - Market Research Reports, Santaris Pharma A/S - Product Pipeline Review - 2014. Description Source: VentureRadar Research / Company Website. in addition to miravirsen, santaris pharma a/s has a robust product pipeline targeting mrnas and micrornas both internally as well as in partnerships and collaborations with miragen therapeutics (cardiovascular diseases), shire plc (rare genetic disorders), pfizer (undisclosed therapeutic areas), glaxosmithkline (viral disease) and enzon - Santaris Pharma A/S initiates Phase 2a clinical trial with miravirsen (SPC3649) to assess safety and tolerability in treatment-naive patients with chronic Hepatitis CHOERSHOLM, Denmark and SAN Global Heparin Sale, Insights Market Research Report 2019-2025, Global BCG Vaccine Sale, Insights Market Research Report 2019-2025, Global Protein expression Market Size study, by System type (Algal-Based Expression Systems, Cell-Free Expression Systems, Insect Cell Expression Systems, Mammalian Cell Expression Systems, Prokaryotic Expression Systems, Yeast Expression Systems), by Product and Service (Competent Cells, Expression Vectors, Instruments, Reagents, Services) By application ( Industrial Applications, Research Applications, Therapeutic Applications) By end user (Academic Research Institutes, Contract Research Organizations, Pharmaceutical and Biotechnology Companies & Other End Users), and Regional Forecasts 2019-2026, Global Wearable Medical Device Market Report 2019, Competitive Landscape, Trends and Opportunities, Global Physiological Sea Water Nasal Spray Market Report 2019, Competitive Landscape, Trends and Opportunities, Global Disposable Sterile Syringe & Needle Market Report 2019, Competitive Landscape, Trends and Opportunities. Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. - As at June It is designed to target the viral mRNA and therefore provides for low off-target effects. San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. Discover our pipeline . Dog kom selskabet i gr med en opdateret pipeline Hanne Damgaard Jensen synes godt om dette . Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. After M&A, selloffs, cost cuts and therapeutic rejigs, the companies on this list may largely wear the same names, but none entered it looking exactly .. Bioventus is a global leader of innovations for active healing and surgical orthobiologics with a comprehensive portfolio of clinically efficacious and cost-effective solutions for patients . . PDF. 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